Using new intelligent manufacturing system can improve the production efficiency and product quality, and improve the adaptability and flexibility of the supply structure of manufacturing industry.Taking the Internet of Things (IoT) as the core, an intelligent manufacturing system of the IoT based on Niagara under the Unity 3D environment was proposed.Based on the threelayer architecture of the IoT, software secondary development was carried out,the compatibility among various module protocols was realized.Then the intelligent manufacturing was realized.