Taking the flexible manufacturing line of multi-robot as the object of study, a scheme of automatic line modeling and virtual production for multi-robot based on using SolidWorks and RobotStudio is presented. Firstly, the production line layout was constructed, followed by the design of the special fixture for the robot for loading and down loading, based on the production line for continuous operation, a simulation of Input/Output (I/O) signal and dynamic Smart components were created, and finally the off-line programming and Simulation of production line were realized. The simulation results show that the robot speed trajectory and the production time can be dynamically output by changing the parameters such as robot Tool Center Point (TCP) speed in real time. The design scheme can provide a theoretical basis and experimental platform for the popularization and application of multi-robot automatic production line in modern industrial manufacturing field.