In order to improve the production efficiency, the unmanned automatic factory is developed. The motion control development system, the computer numerical control (CNC) system, the machining center of machine tool body and the four-degree-of-freedom (4-DOF) manipulator automatic feeding mechanism were used as the development platform. Through the motion control development system, the transport route planning of the 4-DOF manipulator was designed, in collaborative of the CNC system and machining center of machine tool body to form a flexible manufacturing unit (FMU). So that the platform has automatic feeding, automatic clamping, automatic processing, and automatic cutting function for the transformation and upgrading of traditional manufacturing technology to provide a certain technical guidance effect.