In order to obtain the vibration response of the support beam of the helicopter rescue simulator under the excitation of simulator and provide a reference for further research on mitigating the vibration of the beam, the finite element model of the support beam was established in ANSYS Workbench, and the random vibration characteristics of the beam were obtained through modal analysis and random vibration response analysis. The numerical model of the natural frequency of the beam was established, and the modal analysis of the beam considering the concentrated mass was carried out by using the pre-stress module of ANSYS. The simulation results of the natural frequency of the beam were compared with the calculated values of the numerical modeling, and the error is less than 1%. Based on the modal analysis, the ANSYS simulation model of the crown block beam considering the dynamics of the helicopter rescue simulator was further established by using the ANSYS random vibration response module, including the beam excitation force model and the beam dynamic response model. The vibration state of the crown block beam under the random load of the helicopter simulator was obtained and compared with the test results to verify the correctness of the model. The results show that the vibration response curves obtained by ANSYS are in good agreement with the experimental results, which verifies the adaptability of this method to solve the random vibration response of the beam.It provides reference for solving the interference problem of the flexible base to the moving platform in the future.