Aiming at the oil cavitation phenomenon in the cylinder block of high pressure axial piston pump,the suppression of cavitation by the cavitation resistance structure of inclined plunger cavity and waist hole in the cylinder block was analyzed.Based on Pumplinx simulation platform,the gas volume fraction in the plunger cavity of the piston pump were simulated and analyzed.The suppression of oil cavitation by the tilt angle of cylinder block plunger cavity and waist hole were investigated respectively.Kriging interpolation was used to predict the unknown parameters adjacent to known parameters,and the optimal cavitation resistance structural parameters were resolved.The results show that the optimal incline angle of the waist hole and the plunger cavity is 75.3° and 9°,and the gas volume fraction in the plunger cavity decreases by 1.2% and 1.7% respectively.